Description

Cyclo(-Ser-Tyr) is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), derived from the amino acids L-Serine and L-Tyrosine. This compound is of significant interest in pharmaceutical research and development due to its role as a potential pharmacophore and its presence as a degradation product or impurity in peptide-based therapeutics. It serves as a critical building block and reference standard for researchers and manufacturers in the biotechnology and fine chemical sectors. Key industries that utilize this high-purity biochemical include pharmaceutical R&D, academic research institutions, and companies specializing in advanced peptide synthesis.

Application

• Pharmaceutical Reference Standard: Used for the identification, qualification, and quantification of related substances in peptide drug products and active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a model compound for studying the stability, degradation pathways, and structure-activity relationships (SAR) of cyclic peptides.
• Peptide Synthesis Intermediate: Acts as a constrained scaffold or a specialized building block in the synthesis of more complex peptide analogs and drug candidates.
• Quality Control & Analytical Testing: Employed in method development and validation for HPLC, LC-MS, and other analytical techniques within QC/QA laboratories.
• Academic & Discovery Chemistry: Utilized in medicinal chemistry programs to explore new therapeutic agents based on the diketopiperazine core structure.

Basic Information

Product Name	Cyclo(-Ser-Tyr)
CAS No.	21754-31-4
Molecular Formula	C12H14N2O4
Molecular Weight	250.25 g/mol
Synonyms	Cyclo(L-seryl-L-tyrosyl); L-Tyrosyl-L-serine anhydride; 3,6-Bis(4-hydroxyphenyl)-2,5-piperazinedione; Cyclo(Ser-Tyr); c(Ser-Tyr); Ser-Tyr Diketopiperazine; DKP-Ser-Tyr; L-Seryl-L-tyrosine cyclic dipeptide
EINECS	Contact for details

Quality Control

Our Cyclo(-Ser-Tyr) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.