Description

(2S,4R)-2-Amino-4-Hydroxypentanoic Acid CAS NO 21704-88-1 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with precise three-dimensional structures. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel active pharmaceutical ingredients (APIs), peptide mimetics, and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Research & Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce specific stereocenters and functional groups into peptide chains.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme inhibition assays.
• Asymmetric Catalysis: Employed as a chiral ligand or auxiliary in asymmetric synthesis to induce enantioselectivity.
• Agrochemical Development: A building block for creating novel, chiral active ingredients for crop protection products.
• Diagnostic Reagents: Utilized in the development of specialized reagents and probes for clinical diagnostics.

Basic Information

Product Name	(2S,4R)-2-Amino-4-Hydroxypentanoic Acid
CAS No.	21704-88-1
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2S,4R)-2-Amino-4-hydroxypentanoic acid; 4-Hydroxy-L-isoleucine; (2S,4R)-4-Hydroxyisoleucine; L-4-Hydroxyisoleucine; (4R)-4-Hydroxy-L-isoleucine; 2-Amino-4-hydroxypentanoic acid; (2S,4R)-2-Amino-4-hydroxypentanoic acid
EINECS	Contact for details

Quality Control

Our (2S,4R)-2-Amino-4-Hydroxypentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (diastereomeric excess)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.