Description

α-Methylcholine is a choline derivative and a structural analog of the essential neurotransmitter acetylcholine. This compound matters as a valuable biochemical tool and a key intermediate in the synthesis of more complex cholinergic agents and pharmaceuticals. It is primarily needed by research institutions and pharmaceutical companies for use in neuroscience studies, metabolic pathway investigations, and the development of novel therapeutic compounds.

Application

• Biochemical Research: Used as a reference standard and a precursor in studies of cholinergic systems, neurotransmission, and enzyme kinetics (e.g., choline acetyltransferase).
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of specialized drugs targeting neurological and cognitive functions.
• Metabolic Studies: Employed in research to understand the role of choline analogs in cellular metabolism and lipid biochemistry.
• Diagnostic Agent Development: Investigated for potential use in creating imaging agents or probes for studying choline uptake in tissues.
• Academic & Industrial R&D: A key material for universities and corporate R&D labs exploring new applications in neurochemistry and medicinal chemistry.

Basic Information

Product Name	α-Methylcholine
CAS No.	21618-46-2
Molecular Formula	C6H16NO+ (typically as a salt, e.g., chloride or iodide)
Molecular Weight	118.20 g/mol (for the cation)
Synonyms	(2-Hydroxypropyl)trimethylammonium; α-Methylcholine; 2-Hydroxy-N,N,N-trimethyl-1-propanaminium; NSC 169865; Choline, α-methyl-; 1-Propanaminium, 2-hydroxy-N,N,N-trimethyl-
EINECS	Contact for details

Quality Control

Our α-Methylcholine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by HPLC or titration), identification (by IR/NMR), and impurity profiles. Our quality commitment supports research reproducibility and compliance with good laboratory practice (GLP) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.