Description

(2S)-2-Amino-5-(Dimethylamino)-5-Oxopentanoic Acid CAS NO 21432-98-4 is a high-purity, non-proteinogenic amino acid derivative characterized by its unique dimethylamino and oxopentanoic acid functional groups. This compound is a critical chiral building block and intermediate in advanced organic synthesis, offering precise stereochemical control for complex molecule construction. It is primarily utilized by research institutions and pharmaceutical manufacturers in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in oncology and neurology research.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce specific structural motifs and modify peptide properties.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme inhibition assays.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in catalytic asymmetric reactions to induce stereoselectivity.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel chelating ligands and organocatalysts.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and chemical biology for exploring new molecular entities.

Basic Information

Item	Detail
Product Name	(2S)-2-Amino-5-(Dimethylamino)-5-Oxopentanoic Acid
CAS No.	21432-98-4
Molecular Formula	C7H14N2O3
Molecular Weight	174.20 g/mol
Synonyms	D-2-Amino-5-(dimethylamino)-5-oxopentanoic acid; (S)-2-Amino-5-(dimethylamino)-5-oxopentanoic acid; L-Glutamine, N5,N5-dimethyl-; N5,N5-Dimethyl-L-glutamine; (2S)-2-Amino-5-(dimethylamino)-5-oxopentanoate; DMG; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-5-(Dimethylamino)-5-Oxopentanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.