Description

Heparin, Sodium, Low Molecular Weight is a sulfated glycosaminoglycan anticoagulant derived from porcine intestinal mucosa. This refined low molecular weight fraction offers a more predictable pharmacokinetic profile and reduced risk of side effects compared to unfractionated heparin, making it a critical active pharmaceutical ingredient (API). It is essential for manufacturers in the pharmaceutical and biotechnology sectors developing antithrombotic and therapeutic formulations.

Application

• Anticoagulant Drug Production: Primary API for the manufacture of injectable anticoagulant and antithrombotic medications.
• Medical Device Coatings: Used to create biocompatible, blood-compatible surfaces on catheters, stents, and extracorporeal circuits.
• Research & Diagnostic Reagents: Serves as a key component in biochemical research, cell culture media supplements, and in vitro diagnostic assays.
• Therapeutic Heparin Derivatives: Intermediate for the synthesis of further refined heparin-based therapeutics.

Basic Information

Product Name	Heparin, Sodium, Low Molecular Weight
CAS No.	21416-88-6
Molecular Formula	(C12H19NO20S3)n • xNa
Molecular Weight	Average MW ~ 4500-5000 Da (Grade Dependent)
Synonyms	Low Molecular Weight Heparin Sodium; LMWH; Enoxaparin Sodium (related); Dalteparin Sodium (related); Nadroparin Calcium (related); Tinzaparin Sodium (related); Heparinoid; Sodium Heparin Low Molecular Weight Fraction
EINECS	Contact for details

Quality Control

Our Heparin, Sodium, Low Molecular Weight is produced and tested under strict quality systems. Each batch is analyzed to ensure it meets stringent specifications for identity, purity, potency, and impurity profiles, aligning with pharmacopeial standards. A comprehensive Certificate of Analysis (COA) detailing results for anti-Factor Xa activity, anti-Factor IIa activity, molecular weight distribution, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White or off-white powder
Identification (IR)	Conforms to Standard
Anti-Factor Xa Activity	90 - 110 IU/mg
Anti-Factor IIa Activity	20 - 35 IU/mg
Anti-Factor Xa / IIa Ratio	> 1.5
Molecular Weight Distribution	> 60% between 2000 - 8000 Da
Protein Content	< 0.1%
Heavy Metals	< 20 ppm
Bacterial Endotoxins	< 0.1 IU/anti-Xa IU
pH (Solution)	5.5 - 7.5
Loss on Drying	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.