Description

S(-)-α-Amino-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinepropanoic Acid is a high-purity, chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because it serves as a critical building block for the development of novel, optically active drug candidates, particularly in antiviral and anticancer research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for its role in creating enantiomerically pure molecules, where its specific stereochemistry is essential for biological activity and regulatory approval.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of nucleoside analogs and other bioactive molecules.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral replication mechanisms.
• Oncology Therapeutics: Serves as a precursor in the creation of chemotherapeutic agents designed for targeted action.
• Biochemical Research: Employed in enzymatic studies and as a standard for analytical method development in chiral separations.
• Peptidomimetics: Incorporated into the design of peptide-like compounds to enhance stability and bioavailability.
• Asymmetric Synthesis: Utilized as a starting material or reagent in catalytic asymmetric reactions to construct complex molecular architectures.

Basic Information

Product Name	S(-)-α-Amino-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinepropanoic Acid
CAS No.	21416-43-3
Molecular Formula	C7H9N3O4
Molecular Weight	199.16 g/mol
Synonyms	(S)-2-Amino-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid; L-2,4-Dioxopyrimidinepropanoic acid; (S)-1-(1-Carboxy-2-aminoethyl)uracil; L-Uracil-1-ylalanine; S-Uracilalanine; (-)-Uracil-1-ylalanine; 1-(S)-1-Carboxy-2-aminoethyluracil; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our S(-)-α-Amino-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinepropanoic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.