Description

n-Myristoyl-L-Serine is a high-purity, synthetic amino acid derivative where the myristoyl (tetradecanoyl) fatty acid chain is conjugated to the serine backbone. This molecular structure imparts unique amphiphilic properties, making it a valuable intermediate for advanced synthesis and formulation. It is primarily utilized in the research and development of bioactive peptides, specialized surfactants, and high-performance cosmetic ingredients. Industries seeking tailored molecular building blocks for pharmaceuticals, personal care, and specialty chemicals will find this compound of significant interest.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of lipopeptide drugs, prodrugs, and bioactive conjugates to enhance cell permeability.
• Cosmetic & Personal Care Actives: Used in the formulation of high-end skin care products as a moisturizing agent, emulsifier, or a precursor for skin-restorative peptides.
• Biochemical Research: Essential reagent in studying protein lipidation (N-myristoylation), cell signaling pathways, and membrane-associated processes.
• Surfactant & Detergent Synthesis: Serves as a raw material for producing mild, biodegradable, and specialty surfactants with low irritation potential.
• Peptide Synthesis: A protected serine derivative used in solid-phase and solution-phase peptide synthesis to introduce lipophilic character.
• Nanotechnology & Drug Delivery: Component in the design of lipid-based nanoparticles, liposomes, and other delivery systems for targeted therapeutics.

Basic Information

Product Name	n-Myristoyl-L-Serine
CAS No.	21394-57-0
Molecular Formula	C17H33NO4
Molecular Weight	315.45 g/mol
Synonyms	L-Serine, N-(1-oxotetradecyl)-; N-Tetradecanoyl-L-serine; N-Myristoyl-L-serine; Myristoylserine; (2S)-2-(Tetradecanoylamino)-3-hydroxypropanoic acid; Serine myristoyl ester; 21394-57-0; FA 14:0-L-Ser
EINECS	Contact for details

Quality Control

Our n-Myristoyl-L-Serine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity ([α]D)	≥ 99.0% L-Isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.