Description

D(+)-10-Camphorsulfonyl Chloride is a high-purity chiral sulfonyl chloride derivative, widely recognized for its role as a versatile chiral auxiliary and building block in asymmetric synthesis. Its primary value lies in enabling the production of enantiomerically pure compounds, which is critical for the efficacy and safety of advanced pharmaceuticals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a key chiral derivatizing agent for the resolution of racemic mixtures of amines and alcohols.
• As a chiral auxiliary in the synthesis of enantiomerically pure pharmaceutical intermediates, such as β-lactam antibiotics.
• In the preparation of chiral catalysts and ligands for asymmetric hydrogenation and other catalytic reactions.
• For the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs) with defined stereochemistry.
• In agrochemical research for creating chiral herbicides and fungicides.
• As a reagent in academic and industrial research for exploring new asymmetric synthetic methodologies.

Basic Information

Product Name	D(+)-10-Camphorsulfonyl Chloride
CAS No.	21286-54-4
Molecular Formula	C10H15ClO3S
Molecular Weight	250.74 g/mol
Synonyms	(1R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2-sulfonyl chloride; (1R)-(-)-10-Camphorsulfonyl chloride; D-(-)-10-Camphorsulfonyl chloride; (1R,4R)-(-)-10-Camphorsulfonyl chloride; (+)-10-Camphorsulfonyl chloride; (R)-(-)-Camphor-10-sulfonyl chloride; D-Camphor-10-sulfonyl chloride; (1R)-10-Camphorsulfonyl chloride
EINECS	244-309-6

Quality Control

Our D(+)-10-Camphorsulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	64 - 68 °C
Specific Rotation [α]20/D	-20° to -24° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.