Description

Pyr-Phe-Oh CAS NO 21282-12-2 is a high-purity dipeptide derivative, specifically pyroglutamyl-phenylalanine, designed for advanced research and pharmaceutical development. This compound serves as a critical building block and intermediate in the synthesis of complex peptides and peptidomimetics, offering precise structural control. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors focused on drug discovery, proteomics, and biochemical studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of therapeutic peptides and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in proteomics, enzyme-substrate studies, and metabolic pathway analysis.
• Peptide Synthesis: Serves as a protected dipeptide building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Drug Discovery: Employed in high-throughput screening and structure-activity relationship (SAR) studies for novel drug candidates.
• Cosmetic Peptides: Potential intermediate for the development of bioactive peptides in skincare formulations.
• Academic Research: Utilized in university and institutional labs for teaching and fundamental chemical biology research.

Basic Information

Product Name	Pyr-Phe-Oh
CAS No.	21282-12-2
Molecular Formula	C₁₄H₁₆N₂O₄
Molecular Weight	276.29 g/mol
Synonyms	Pyroglutamyl-Phenylalanine; L-Pyroglutamyl-L-phenylalanine; 5-Oxo-L-prolyl-L-phenylalanine; Pyr-Phe-OH; Pyr-L-Phe-OH; 5-Oxoprolylphenylalanine; H-pGlu-Phe-OH; L-Pyroglutamic Acid-L-Phenylalanine
EINECS	Contact for details

Quality Control

Our Pyr-Phe-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and pharmaceutical intermediates, with specifications tailored to meet rigorous research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.