Description

Pyroglutamylleucine is a dipeptide derivative formed from pyroglutamic acid and leucine. This compound is of significant interest in biochemical research and advanced manufacturing due to its role as a potential bioactive peptide fragment and a key intermediate in peptide synthesis. It is primarily utilized by the pharmaceutical, biotechnology, and nutraceutical industries for applications in drug discovery, proteomics, and the development of specialized nutritional supplements.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex peptides and peptidomimetics for therapeutic development.
• Biochemical Research: Used as a standard or reagent in proteomics research, enzyme studies, and metabolic pathway analysis.
• Cosmetic & Skincare Actives: Incorporated into formulations for its potential moisturizing and skin-conditioning properties as a peptide derivative.
• Nutraceutical Development: Investigated as a component in specialized dietary supplements targeting muscle metabolism and recovery.
• Cell Culture Media: Employed as a defined component in specialized cell culture systems and microbiological media.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Item	Details
Product Name	Pyroglutamylleucine
CAS No.	21282-11-1
Molecular Formula	C11H18N2O4
Molecular Weight	242.27 g/mol
Synonyms	L-Pyroglutamyl-L-leucine; 5-Oxo-L-prolyl-L-leucine; Pyrrolidonecarboxylic acid leucine; pGlu-Leu; (S)-5-Oxo-2-pyrrolidinecarboxylic acid (S)-1-((S)-1-carboxy-3-methylbutyl)carbamoyl]propyl]amide; 5-Oxoprolylleucine; N-(L-5-Oxopyrrolidin-2-carbonyl)-L-leucine
EINECS	Contact for details

Quality Control

Our Pyroglutamylleucine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.