Description

Pyr-Ala-Oh CAS NO 21282-08-6 is a high-purity, protected dipeptide building block, specifically L-Pyroglutamyl-L-alanine, essential for advanced peptide synthesis. This compound is valued for its role in constructing complex peptide sequences with precise stereochemistry and functional group protection. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, peptide-based therapeutic development, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled elongation of peptide chains in automated synthesizers.
• Pharmaceutical Research: Building block for the development of novel peptide drugs, hormones, and enzyme inhibitors.
• Bioconjugation: Used to create peptide tags or linkers for protein labeling and antibody-drug conjugates (ADCs).
• Biochemical Studies: Serves as a substrate or standard in enzymatic assays and metabolic pathway studies.
• Cosmeceutical Peptides: A precursor in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	Pyr-Ala-Oh
CAS No.	21282-08-6
Molecular Formula	C8H12N2O4
Molecular Weight	200.19 g/mol
Synonyms	L-Pyroglutamyl-L-alanine; 5-Oxo-L-prolyl-L-alanine; Pyr-L-Ala-OH; H-Pyr-Ala-OH; (S)-2-((S)-5-Oxopyrrolidine-2-carboxamido)propanoic acid; Pyroglutamylalanine; PG-Ala-OH; L-Pyroglutamic acid-L-alanine
EINECS	Contact for details

Quality Control

Our Pyr-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.