Description

5-Chloro-2-(4-Piperonyl-1-Piperazinyl)Pyrimidine is a high-purity, heterocyclic organic compound featuring a pyrimidine core substituted with a chlorophenyl and a piperonylpiperazine moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and psychotropic therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new bioactive molecules.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Organic Synthesis: Employed in multi-step synthetic routes to create complex heterocyclic compounds for various research applications.

Basic Information

Product Name	5-Chloro-2-(4-Piperonyl-1-Piperazinyl)Pyrimidine
CAS No.	21280-23-9
Molecular Formula	C16H17ClN4O2
Molecular Weight	332.79 g/mol
Synonyms	5-Chloro-2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine; 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-5-chloropyrimidine; 5-Chloro-2-(4-piperonylpiperazino)pyrimidine; 5-Chloro-2-(4-(piperonyl)piperazinyl)pyrimidine; 21280-23-9; 5-Chloro-2-(4-piperonyl-1-piperazinyl)pyrimidine
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-2-(4-Piperonyl-1-Piperazinyl)Pyrimidine adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.