Description

2-(2-Dimethylaminoethoxy)-3-Phenyl-4H-Pyrazino(1,2-A)Pyrimidin-4-One Hydrobromide is a high-purity, complex heterocyclic compound used as a critical intermediate in advanced pharmaceutical research and development. Its value lies in its specific molecular architecture, which makes it a key building block for synthesizing novel active pharmaceutical ingredients (APIs) targeting complex diseases. This product is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Active Pharmaceutical Ingredient (API) Development: Employed in the development and scale-up processes for new chemical entities (NCEs).
• Biochemical Tool Compound: Utilized in vitro and in vivo to study specific biological pathways and validate novel drug targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic & Institutional Research: Used in university laboratories and research institutes for fundamental studies in organic synthesis and pharmacology.

Basic Information

Item	Details
Product Name	2-(2-Dimethylaminoethoxy)-3-Phenyl-4H-Pyrazino(1,2-A)Pyrimidin-4-One Hydrobromide
CAS No.	21271-21-6
Molecular Formula	C₁₈H₂₁BrN₄O₂
Molecular Weight	405.29 g/mol
Synonyms	2-(2-Dimethylaminoethoxy)-3-phenylpyrazino[1,2-a]pyrimidin-4-one hydrobromide; 3-Phenyl-2-[2-(dimethylamino)ethoxy]pyrazino[1,2-a]pyrimidin-4-one hydrobromide; 21271-21-6; Pyrazino[1,2-a]pyrimidin-4-one, 2-[2-(dimethylamino)ethoxy]-3-phenyl-, hydrobromide; UNII-9J6I9Q8F1M; 9J6I9Q8F1M
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Dimethylaminoethoxy)-3-Phenyl-4H-Pyrazino(1,2-A)Pyrimidin-4-One Hydrobromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting regulatory filings for preclinical and clinical development. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and residual solvent analysis are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.