Description

2-(2-(Trifluoromethyl)Phenyl)Acetaldehyde is a specialized fluorinated aromatic aldehyde building block. This compound is valued for its unique trifluoromethylphenyl moiety, which imparts significant lipophilicity and metabolic stability to target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the CF₃ group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals for electronic and optical applications.
• Chemical Biology Probes: Useful for incorporating fluorinated tags into biomolecules for study via techniques like ¹⁹F NMR spectroscopy.

Basic Information

Product Name	2-(2-(Trifluoromethyl)Phenyl)Acetaldehyde
CAS No.	21235-63-2
Molecular Formula	C₉H₇F₃O
Molecular Weight	188.15 g/mol
Synonyms	2-[2-(Trifluoromethyl)phenyl]acetaldehyde; α,α,α-Trifluoro-o-tolualdehyde; 2-(2-Trifluoromethylphenyl)ethanal; o-(Trifluoromethyl)phenylacetaldehyde; 2-(2-Trifluoromethylphenyl)acetaldehyde; 1-(2-Trifluoromethylphenyl)-2-oxoethane; (2-(Trifluoromethyl)phenyl)acetic aldehyde
EINECS	Contact for details

Quality Control

Our 2-(2-(Trifluoromethyl)Phenyl)Acetaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.