Description

Dl-3-Thiolisoleucine CAS NO 21213-64-9 is a sulfur-containing derivative of the branched-chain amino acid isoleucine, characterized by the presence of a thiol group. This modification makes it a valuable building block and intermediate in the synthesis of specialized peptides, pharmaceutical compounds, and biochemical research reagents. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors. The compound's unique structure allows for the introduction of thiol functionality into target molecules, enabling applications in drug discovery and protein engineering.

Application

• Key intermediate in the pharmaceutical synthesis of novel therapeutic peptides and peptidomimetics.
• Building block for research chemicals and biochemical probes used in studying enzyme mechanisms and protein interactions.
• Precursor in the development of specialized amino acid analogs for nutritional and metabolic research.
• Starting material for the synthesis of chiral ligands and catalysts in asymmetric organic synthesis.
• Component in the preparation of custom amino acid derivatives for advanced material science applications.

Basic Information

Product Name	Dl-3-Thiolisoleucine
CAS No.	21213-64-9
Molecular Formula	C6H13NO2S
Molecular Weight	163.24 g/mol
Synonyms	DL-3-Thiolisoleucine; (±)-3-Thiolisoleucine; 3-Mercaptoisoleucine; 2-Amino-3-mercapto-4-methylpentanoic acid; 3-Thiol-DL-isoleucine; DL-3-Mercaptoisoleucine; 4-Methyl-3-mercapto-DL-norvaline; 3-Thiol-DL-alloisoleucine
EINECS	Contact for details

Quality Control

Our Dl-3-Thiolisoleucine is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) documenting all test results are provided to guarantee traceability and consistency. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Due to its property of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain stability and purity. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.