Description

N5-(4,6-Dimethyl-2-Pyrimidinyl)-L-Ornithine Ethyl Ester is a specialized ornithine derivative that serves as a critical building block in advanced organic synthesis and pharmaceutical research. This compound is valued for its role as a key intermediate in the development of novel therapeutic agents, particularly those targeting enzymatic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex bioactive molecules. The product is supplied to meet the stringent purity and consistency requirements of modern drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially enzyme inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Biochemical Tool Compound: Employed in biochemical assays to study specific biological pathways and mechanisms of action.
• Process Chemistry Development: Serves as a standard or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Academic Research: Utilized in university and institutional labs for investigating novel synthetic methodologies and heterocyclic chemistry.
• Custom Synthesis Building Block: Provides a versatile pyrimidinyl-ornithine scaffold for the custom synthesis of specialized compounds for clients.

Basic Information

Product Name	N5-(4,6-Dimethyl-2-Pyrimidinyl)-L-Ornithine Ethyl Ester
CAS No.	21175-12-2
Molecular Formula	C13H22N4O2
Molecular Weight	266.34 g/mol
Synonyms	L-Ornithine, N5-(4,6-dimethyl-2-pyrimidinyl)-, ethyl ester; Ethyl N5-(4,6-dimethyl-2-pyrimidinyl)-L-ornithinate; (S)-2-Amino-5-((4,6-dimethylpyrimidin-2-yl)amino)pentanoic acid ethyl ester; 2-Amino-5-[(4,6-dimethyl-2-pyrimidinyl)amino]pentanoic acid ethyl ester; N5-(4,6-Dimethylpyrimidin-2-yl)-L-ornithine ethyl ester; L-Ornithine ethyl ester derivative; Pyrimidinyl ornithine ester
EINECS	Contact for details

Quality Control

Every batch of N5-(4,6-Dimethyl-2-Pyrimidinyl)-L-Ornithine Ethyl Ester is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to support cGMP and ISO standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.