Description

Z-Dehydro-Ala-Ome CAS NO 21149-17-7 is a specialized, non-proteinogenic amino acid derivative featuring a dehydroalanine moiety protected as a methyl ester. This compound serves as a critical synthetic intermediate and building block in advanced organic and medicinal chemistry. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and biotechnology sectors for the development of novel peptides, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based drugs, enzyme inhibitors, and protease substrates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel therapeutic candidates.
• Peptide Synthesis: Serves as a protected dehydroalanine residue in solid-phase and solution-phase peptide synthesis to introduce conformational constraints.
• Bioconjugation & Probe Development: Useful for creating labeled peptides or affinity probes due to its reactive alkene functionality.
• Agrochemical Research: Intermediate in the synthesis of novel bioactive compounds for crop protection.
• Academic & Institutional R&D: Employed in universities and research institutes for studying peptide chemistry and bioorganic reaction mechanisms.

Basic Information

Product Name	Z-Dehydro-Ala-Ome
CAS No.	21149-17-7
Molecular Formula	C12H13NO4
Molecular Weight	235.24 g/mol
Synonyms	N-Carbobenzoxy-dehydroalanine methyl ester; (Z)-Dehydroalanine methyl ester; N-(Benzyloxycarbonyl)-2,3-didehydroalanine methyl ester; Methyl (Z)-2-[(benzyloxy)carbonyl]aminoacrylate; 2-Propenoic acid, 2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2Z)-; Z-δAla-OMe; N-Cbz-dehydroalanine methyl ester; Benzyloxycarbonyl-dehydroalanine methyl ester
EINECS	Contact for details

Quality Control

Every batch of Z-Dehydro-Ala-Ome is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.