Description

Secretin (1-6) is a bioactive hexapeptide fragment of the gastrointestinal hormone secretin. This compound is of significant interest for its role in stimulating pancreatic bicarbonate secretion and for use as a research tool in studying digestive physiology and hormone-receptor interactions. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in metabolic and gastrointestinal research, drug discovery, and peptide synthesis.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of pancreatic function, fluid secretion, and hormone signaling pathways.
• Drug Discovery & Development: Serves as a key intermediate or pharmacophore in the design and synthesis of novel peptide-based therapeutics targeting digestive disorders.
• Biochemical Assays: Employed in receptor binding studies, enzyme-linked immunosorbent assays (ELISAs), and other in vitro diagnostic tests to investigate secretin activity.
• Academic & Clinical Studies: Facilitates fundamental research into the physiology of the duodenum, stomach, and pancreas, as well as potential clinical applications.
• Peptide Synthesis: Acts as a building block or template for the custom synthesis of longer secretin analogs or related peptide sequences.
• Quality Control: Used as an analytical standard in pharmaceutical quality control laboratories to ensure the purity and potency of secretin-related products.

Basic Information

Product Name	Secretin (1-6)
CAS No.	21012-75-9
Molecular Formula	C31H50N10O11
Molecular Weight	714.8 g/mol
Synonyms	Secretin hexapeptide; H-His-Ser-Asp-Gly-Thr-Phe-OH; Secretin fragment 1-6; Secretin (1-6) amide (common derivative); Gastrointestinal peptide fragment; HSDAFT; SCT(1-6)
EINECS	Contact for details

Quality Control

Our Secretin (1-6) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets high-grade research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.