Description

Cholecystokinin (27-33), T-Butyloxycarbonyl- is a synthetic peptide fragment of the gastrointestinal hormone cholecystokinin, specifically the C-terminal heptapeptide amide sequence protected by a Boc (tert-butyloxycarbonyl) group. This compound is a critical research-grade biochemical tool for studying CCK receptor binding, signal transduction, and the physiological roles of cholecystokinin in digestion and satiety. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, gastroenterology, and metabolic disorder research.

Application

• Neuroscience Research: Used as a selective ligand to study the distribution and function of CCK receptors in the central and peripheral nervous systems.
• Pharmacological Assay Development: Serves as a reference standard and active agent in high-throughput screening (HTS) for drug discovery programs targeting CCK receptors.
• Biochemical Studies: Employed in structure-activity relationship (SAR) studies to understand the bioactive core of cholecystokinin and design peptide analogs.
• Gastrointestinal Physiology Research: Investigates the role of CCK in pancreatic enzyme secretion, gallbladder contraction, and gut motility.
• Metabolic Research: Applied in studies exploring the satiety-inducing effects of CCK and its potential role in obesity and eating disorders.
• Cell Signaling Pathways: Used to activate CCK receptors in vitro to study downstream intracellular signaling cascades.

Basic Information

Product Name	Cholecystokinin (27-33), T-Butyloxycarbonyl-
CAS No.	20987-59-1
Molecular Formula	C44H64N8O11S
Molecular Weight	913.1 g/mol
Synonyms	Boc-CCK-7; Boc-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; tert-Butyloxycarbonyl-Cholecystokinin Fragment 27-33; CCK-7, Boc-; Cholecystokinin (27-33) amide, Nα-(tert-butyloxycarbonyl)-; Boc-[Tyr(SO3H)27]-CCK (27-33); CCK heptapeptide, Boc-protected; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (Boc-Asp-)
EINECS	Contact for details

Quality Control

Our Cholecystokinin (27-33), T-Butyloxycarbonyl- is manufactured under strict quality systems suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.