Description

2-(1-Piperazinyl)Pyrimidine is a versatile heterocyclic organic compound featuring a pyrimidine core substituted with a piperazine moiety, serving as a crucial building block in advanced chemical synthesis. Its bifunctional structure makes it an invaluable intermediate for creating complex molecules with targeted biological or material properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the piperazinyl-pyrimidine scaffold contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, or metal-organic frameworks (MOFs) due to its rigid, nitrogen-rich structure.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	2-(1-Piperazinyl)Pyrimidine
CAS No.	20980-22-7
Molecular Formula	C8H12N4
Molecular Weight	164.21 g/mol
Synonyms	2-Piperazin-1-ylpyrimidine; 2-Piperazinylpyrimidine; 1-(Pyrimidin-2-yl)piperazine; Pyrimidine, 2-(1-piperazinyl)-; 2-(Piperazin-1-yl)pyrimidine; NSC 163082; 20980-22-7
EINECS	Contact for details

Quality Control

We supply 2-(1-Piperazinyl)Pyrimidine in high-purity grades suitable for research and industrial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. For specific pharmacopeial (e.g., USP) or custom grade requirements, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.