Description

N(G)-Monoethylarginine is a chemically modified derivative of the amino acid L-arginine, featuring an ethyl group on the guanidino nitrogen. This specific modification makes it a valuable biochemical tool and a key intermediate in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for investigating nitric oxide synthase (NOS) pathways and developing novel therapeutic agents. Our supply ensures high purity and batch-to-batch consistency critical for sensitive applications.

Application

• Biochemical Research: Acts as a selective inhibitor in studies of nitric oxide synthase (NOS) isoforms to understand cardiovascular and neurological functions.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of novel drug candidates targeting conditions related to nitric oxide dysregulation.
• Enzyme Kinetics Studies: Used to probe the active sites and catalytic mechanisms of arginine-utilizing enzymes.
• Diagnostic Reagent Development: Employed in the formulation of assay kits and reagents for research and clinical diagnostics.
• Academic & Institutional Research: Supports fundamental research in universities and institutes focused on cell signaling, metabolism, and disease pathology.
• Pre-clinical Development: Used in animal model studies to validate therapeutic hypotheses and assess drug efficacy and safety profiles.

Basic Information

Product Name	N(G)-Monoethylarginine
CAS No.	20933-81-7
Molecular Formula	C8H18N4O2
Molecular Weight	202.25 g/mol
Synonyms	NG-Monoethyl-L-arginine; L-NG-Monoethylarginine; Nω-Ethyl-L-arginine; 2-Amino-5-[(aminoethylamino)imino]pentanoic acid; N-Ethyl-L-arginine; NG-Ethylarginine; L-NG-Ethylarginine; NMMA analog
EINECS	Contact for details

Quality Control

Our N(G)-Monoethylarginine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. For custom purity requirements or specific pharmacopeial standards (e.g., USP), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: +22.0° to +26.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.