Description

Thymine-1-Acetic Acid is a key pyrimidine derivative, chemically known as 2-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid. This compound serves as a versatile building block in organic synthesis and pharmaceutical research, enabling the development of novel nucleoside analogs and other bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and academic research institutions focused on antiviral, anticancer, and diagnostic agent development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of modified nucleosides and nucleotides for antiviral and anticancer drug discovery.
• Bioconjugation Chemistry: Used to introduce a thymine moiety with a carboxylic acid linker for coupling with peptides, proteins, or other biomolecules.
• Probe and Diagnostic Development: Serves as a starting material for creating labeled probes or diagnostic agents in molecular biology.
• Academic Research: Employed in studies exploring DNA/RNA chemistry, enzyme mechanisms, and the development of novel therapeutic agents.
• Chemical Biology Tool: Facilitates the study of nucleic acid interactions and the design of enzyme inhibitors.
• Material Science: Potential use in the development of functionalized polymers or surfaces with specific nucleobase recognition properties.

Basic Information

Product Name	Thymine-1-Acetic Acid
CAS No.	20924-05-4
Molecular Formula	C7H8N2O4
Molecular Weight	184.15 g/mol
Synonyms	2-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid; 1-Carboxymethylthymine; N1-Carboxymethylthymine; Thymin-1-ylacetic Acid; (2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetic Acid; 1-(Carboxymethyl)thymine; Thymine-N1-acetic Acid
EINECS	Contact for details

Quality Control

Our Thymine-1-Acetic Acid is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.