Description

Boc-Tyr(Boc)-Oh is a protected derivative of the amino acid tyrosine, widely used as a critical building block in peptide synthesis. Its primary value lies in providing orthogonal protection for the tyrosine side chain hydroxyl group and the α-amino group, enabling precise and sequential peptide chain assembly. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity intermediates for the development of therapeutic peptides and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of tyrosine residues into peptide sequences.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing peptides and peptide conjugates.
• Pharmaceutical Research: Serves as a building block for the research and development of novel peptide-based drugs and APIs (Active Pharmaceutical Ingredients).
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for diagnostic or therapeutic applications.
• Combinatorial Chemistry: Employed in libraries for drug discovery to explore structure-activity relationships.
• Academic & Institutional Research: Used in biochemical and organic chemistry laboratories for studying peptide structure and function.

Basic Information

Product Name	Boc-Tyr(Boc)-Oh
CAS No.	20866-48-2
Molecular Formula	C₁₉H₂₇NO₇
Molecular Weight	381.42 g/mol
Synonyms	N-α-tert-Butoxycarbonyl-O-tert-butyl-L-tyrosine; Boc-L-Tyrosine(Boc)-OH; Boc-Tyr(tBu)-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid; tert-Butyl N-[(1S)-1-carboxy-2-[4-[(2-methylpropan-2-yl)oxy]phenyl]ethyl]carbamate; Boc-O-t-butyl-L-tyrosine; L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our Boc-Tyr(Boc)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive applications like peptide synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and stored in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.