Description

Digoxin CAS NO 20830-75-5 is a purified cardiac glycoside derived from the leaves of the *Digitalis lanata* plant. This high-purity active pharmaceutical ingredient (API) is critical for the precise formulation of life-saving cardiovascular medications. It is primarily required by pharmaceutical manufacturers and research institutions for the production of treatments for various heart conditions, including atrial fibrillation and heart failure.

Application

• Pharmaceutical API: Primary use as the active ingredient in tablet, capsule, and injectable formulations for cardiac therapy.
• Cardiac Arrhythmia Treatment: Formulation of medications to control ventricular rate in patients with chronic atrial fibrillation.
• Heart Failure Management: Manufacture of drugs to improve symptoms and increase exercise capacity in patients with mild to moderate heart failure.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical labs.
• Biochemical Research: Used in pharmacological studies to investigate the mechanism of action of cardiac glycosides on the sodium-potassium ATPase pump.
• Veterinary Medicine: Employed in certain veterinary cardiac treatments under strict dosage control.

Basic Information

Product Name	Digoxin
CAS No.	20830-75-5
Molecular Formula	C41H64O14
Molecular Weight	780.95 g/mol
Synonyms	Digoxin; Lanoxin; Cardoxin; Digacin; 12β-Hydroxydigitoxin; (3β,5β,12β)-3-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
EINECS	244-068-1

Quality Control

Our Digoxin is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including identity, purity, and impurity profile confirmation. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and regulatory support for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Specific Optical Rotation	+13.5° to +15.5° (c = 1 in pyridine)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.