Description

3,5-Difluorosulfanilic Acid (So3H=1) is a high-purity, functionalized aromatic sulfonic acid derivative, distinguished by its strategic fluorine substitution. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and fluorine-containing therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, leveraging the bioactivity-enhancing properties of fluorine.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and pigments, where the sulfonic acid group improves solubility and the fluorine atoms alter color fastness and properties.
• Liquid Crystal & OLED Materials: Intermediate for creating fluorine-containing components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Acts as a monomer or functionalizing agent to introduce sulfonic acid and fluorine groups into polymers, enhancing characteristics like hydrophilicity or chemical resistance.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	3,5-Difluorosulfanilic Acid (So3H=1)
CAS No.	20804-28-8
Molecular Formula	C6H5F2NO3S
Molecular Weight	209.17 g/mol
Synonyms	4-Amino-3,5-difluorobenzenesulfonic Acid; Benzenesulfonic acid, 4-amino-3,5-difluoro-; 3,5-Difluoro-4-aminobenzenesulfonic Acid; 3,5-Difluoroaniline-4-sulfonic Acid; 4-Amino-3,5-difluorophenylsulfonic Acid; 20804-28-8; 3,5-DFSA
EINECS	Contact for details

Quality Control

Our 3,5-Difluorosulfanilic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.