Description

(+)-3-Methylene-L-Norvaline CAS NO 20772-41-2 is a non-proteinogenic amino acid derivative of significant interest in advanced pharmaceutical research and development. This chiral building block is valued for its unique structural features, which enable the synthesis of novel peptide analogs and bioactive compounds. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on drug discovery, proteomics, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Proteomics & Biochemical Research: Used as a building block for creating custom peptides and molecular probes to study protein structure, function, and interactions.
• Enzyme Inhibitor Development: Incorporated into substrate analogs to design and synthesize potent, selective inhibitors for target enzymes.
• Metabolic Pathway Studies: Employed as a tracer or analog in research investigating amino acid metabolism and related biological pathways.
• Fine Chemical Synthesis: Serves as a specialized starting material for the preparation of complex, high-value organic molecules in custom synthesis projects.

Basic Information

Product Name	(+)-3-Methylene-L-Norvaline
CAS No.	20772-41-2
Molecular Formula	C₆H₁₁NO₂
Molecular Weight	129.16 g/mol
Synonyms	(2S)-2-Amino-3-methylidenepentanoic acid; L-3-Methylenenorvaline; (S)-2-Amino-3-methylenepentanoic acid; 3-Methylene-L-norvaline; (S)-3-Methylenenorvaline; Norvaline, 3-methylene-, L-; UNII-9J8P6K8U4Q
EINECS	Contact for details

Quality Control

Our (+)-3-Methylene-L-Norvaline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.