Description

H-Trp-Gly-Gly-Oh is a synthetic tripeptide composed of Tryptophan (Trp) and two Glycine (Gly) residues with a free carboxylic acid terminus. This compound serves as a crucial building block and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in peptide synthesis, neuropeptide studies, and drug discovery programs.

Application

• Biochemical Research: As a key intermediate or reference standard in peptide synthesis and structure-activity relationship (SAR) studies.
• Neuroscience Studies: Investigation of peptide interactions with neurotransmitter systems due to the presence of the tryptophan moiety.
• Pharmaceutical Development: Serving as a precursor or model compound in the development of novel peptide-based therapeutics.
• Enzyme Substrate/Analogue: Potential use as a substrate for studying enzyme kinetics or as an inhibitor analogue in protease research.
• Academic Research: Fundamental studies in organic chemistry, peptide chemistry, and medicinal chemistry within university laboratories.
• Quality Control: Use as an analytical standard for HPLC or LC-MS method development and validation in QC laboratories.

Basic Information

Item	Details
Product Name	H-Trp-Gly-Gly-Oh
CAS No.	20762-31-6
Molecular Formula	C16H20N4O4
Molecular Weight	332.35 g/mol
Synonyms	Tryptophylglycylglycine; Glycylglycyl-L-tryptophan; L-Tryptophylglycylglycine; H-Tryptophan-Glycine-Glycine-OH; Trp-Gly-Gly; WGG; TGG; N-(3-Indolylmethyl)glycylglycine
EINECS	Contact for details

Quality Control

Our H-Trp-Gly-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.