Description

H-Ala-Asp-Oh CAS NO 20727-65-5 is a high-purity, protected dipeptide building block, specifically L-Alanine-L-Aspartic Acid, where the C-terminal carboxylic acid is protected. This compound is a critical intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, development of bioactive peptides, and proteomics research.

Application

• Pharmaceutical Research & Development: A key building block for the synthesis of novel therapeutic peptides targeting metabolic disorders, neurological conditions, and cancer.
• Peptide Library Synthesis: Used in combinatorial chemistry to create diverse peptide libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Bioconjugation & Labeling: Serves as a spacer or linker molecule in the preparation of peptide-protein conjugates, vaccines, and diagnostic agents.
• Enzyme Substrate & Inhibitor Design: Employed in the development of specific substrates or inhibitors for proteases like caspases and other aspartic acid-processing enzymes.
• Academic & Biochemical Research: Fundamental tool for studying peptide structure, folding, and interactions in academic and industrial biochemistry labs.
• Cosmeceutical Peptide Synthesis: Potential raw material for the synthesis of bioactive peptides used in advanced skincare and cosmetic formulations.

Basic Information

Item	Detail
Product Name	H-Ala-Asp-Oh
CAS No.	20727-65-5
Molecular Formula	C7H12N2O5
Molecular Weight	204.18 g/mol
Synonyms	L-Alanyl-L-aspartic acid; H-Ala-Asp-OH; Ala-Asp; Alanine-Aspartic Acid; L-Ala-L-Asp; N-(2-{[(2S)-2-aminopropanoyl]amino}-1-carboxyethyl)-L-aspartic acid; Aspartylalanine; Protected Ala-Asp dipeptide
EINECS	Contact for details

Quality Control

Every batch of H-Ala-Asp-Oh is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity for your critical research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are supplied with each shipment. Our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 102.0%
Specific Rotation	-20° to -30° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.