Description

2-Amino-3-(4-Hydroxy-3,5-Diiodophenyl)Propanoic Acid Hydrate is a halogenated derivative of the essential amino acid tyrosine, distinguished by its two iodine atoms which confer unique biochemical properties. This compound is critical for research and development in the life sciences, particularly in the study of thyroid hormone synthesis and metabolism. It serves as a key intermediate and reference standard for pharmaceutical, diagnostic, and biochemical applications where precise molecular structure is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis and research of thyroid hormone analogs and related therapeutic agents.
• Biochemical Research: Acts as a crucial substrate or inhibitor in enzymatic studies related to tyrosine metabolism and iodination processes.
• Diagnostic Agent Development: Serves as a precursor or reference compound in the development of radioiodinated tracers for medical imaging.
• Reference Standard: Provides a high-purity standard for analytical methods, including HPLC and mass spectrometry, in quality control laboratories.
• Metabolic Pathway Studies: Utilized in in-vitro and in-vivo research to investigate the biosynthesis of thyroid hormones and other iodinated biomolecules.
• Academic & Industrial R&D: A fundamental building block for novel compound libraries in medicinal chemistry and drug discovery programs.

Basic Information

Product Name	2-Amino-3-(4-Hydroxy-3,5-Diiodophenyl)Propanoic Acid Hydrate
CAS No.	20704-71-6
Molecular Formula	C9H9I2NO3 · xH2O
Molecular Weight	433.00 (Anhydrous basis)
Synonyms	3,5-Diiodotyrosine Hydrate; DIT Hydrate; 4-Hydroxy-3,5-diiodophenylalanine Hydrate; 2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid monohydrate; (2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid hydrate; L-3,5-Diiodotyrosine Hydrate; β-(3,5-Diiodo-4-hydroxyphenyl)-L-alanine Hydrate; 20704-71-6
EINECS	Contact for details

Quality Control

Our 2-Amino-3-(4-Hydroxy-3,5-Diiodophenyl)Propanoic Acid Hydrate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.