Description

Z-Trp-Nh2 is a protected derivative of the essential amino acid tryptophan, specifically the Z-protected tryptophan amide. This compound is a crucial chiral building block and intermediate in the synthesis of complex peptides and peptidomimetics, offering high purity and stereochemical integrity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate protected tryptophan residues.
• Biochemical Research: Serves as a standard or reagent in proteomics research and enzyme substrate studies.
• Fine Chemical Production: Intermediate in the manufacture of specialized agrochemicals, dyes, and advanced materials.
• Academic & R&D Laboratories: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	Z-Trp-Nh2
CAS No.	20696-64-4
Molecular Formula	C19H19N3O3
Molecular Weight	337.37 g/mol
Synonyms	Nα-Carbobenzoxy-L-tryptophanamide; N-Cbz-L-tryptophan amide; Z-L-Tryptophan amide; CBZ-L-Tryptophanamide; (S)-2-(((Benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanamide; Benzyl N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate; Z-Tryptophan-NH2; Cbz-Trp-NH2
EINECS	Contact for details

Quality Control

Our Z-Trp-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests to ensure compliance with high-grade standards. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.