Description

5-Chloro-6-Methyl-2-Phenylpyrimidin-4(3H)-One is a high-purity pyrimidinone derivative, a key heterocyclic building block valued for its structural versatility in advanced organic synthesis. This compound matters because it serves as a critical intermediate for developing active pharmaceutical ingredients (APIs) and functional agrochemicals, where precise molecular architecture is paramount. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A valuable reagent for methodology development and exploring new chemical reactions in academic and industrial R&D laboratories.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects requiring reliable, high-quality advanced intermediates.

Basic Information

Product Name	5-Chloro-6-Methyl-2-Phenylpyrimidin-4(3H)-One
CAS No.	20551-31-9
Molecular Formula	C11H9ClN2O
Molecular Weight	220.65 g/mol
Synonyms	5-Chloro-6-methyl-2-phenyl-3,4-dihydropyrimidin-4-one; 5-Chloro-6-methyl-2-phenyl-4(3H)-pyrimidinone; 4(3H)-Pyrimidinone, 5-chloro-6-methyl-2-phenyl-; 2-Phenyl-5-chloro-6-methylpyrimidin-4(3H)-one; 5-Chloro-6-methyl-2-phenyl-4-pyrimidinol; 5-Chloro-6-methyl-2-phenylpyrimidin-4-ol
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Methyl-2-Phenylpyrimidin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications requiring high-purity intermediates, from early-stage research to commercial-scale GMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.