Description

Z-Tyr-Ser-Oh is a protected dipeptide derivative, specifically the C-terminal carboxylic acid of the tyrosine-serine sequence with a benzyloxycarbonyl (Z) protecting group on the N-terminus. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of longer, more complex peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the custom synthesis of peptides for research and development.
• Pharmaceutical Intermediates: Serves as a key intermediate in the production of potential peptide-based drugs targeting various diseases.
• Biochemical Research: Used in studies of enzyme-substrate interactions, protein folding, and signal transduction pathways involving tyrosine and serine residues.
• Antigen Synthesis: Employed in the creation of peptide antigens for antibody production and immunological assays.
• Proteomics and Biomarker Discovery: A tool for synthesizing standardized peptides used as internal standards in mass spectrometry.
• Cosmeceutical Peptide Development: A precursor in the research and formulation of bioactive peptides for skincare applications.

Basic Information

Product Name	Z-Tyr-Ser-Oh
CAS No.	20448-71-9
Molecular Formula	C₂₀H₂₂N₂O₇
Molecular Weight	402.40 g/mol
Synonyms	N-Benzyloxycarbonyl-O-benzyl-L-tyrosyl-L-serine; Z-Tyr(Bzl)-Ser-OH; Z-O-Benzyl-L-tyrosyl-L-serine; N-Cbz-O-benzyl-L-tyrosyl-L-serine; Cbz-Tyr(Bzl)-Ser-OH; Z-L-Tyrosine(O-benzyl)-L-serine; Nα-Carbobenzoxy-O-benzyl-L-tyrosyl-L-serine; (2S)-2-[[(2S)-2-(Benzyloxycarbonylamino)-3-(4-benzyloxyphenyl)propanoyl]amino]-3-hydroxypropanoic acid
EINECS	Contact for details

Quality Control

Our Z-Tyr-Ser-Oh is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.