Description

2,4,6-Trichloro-5-(2-Acetic Acid) Pyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its reactive chlorinated sites and carboxylic acid functionality make it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Used in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for creating complex heterocyclic compounds.
• Material Science Research: Intermediate for developing functional polymers, liquid crystals, and organic electronic materials.
• Bioconjugation Chemistry: The carboxylic acid group enables coupling to biomolecules for probe and linker development.

Basic Information

Product Name	2,4,6-Trichloro-5-(2-Acetic Acid) Pyrimidine
CAS No.	20401-33-6
Molecular Formula	C6H3Cl3N2O2
Molecular Weight	241.46 g/mol
Synonyms	5-(Carboxymethyl)-2,4,6-trichloropyrimidine; 2,4,6-Trichloro-5-pyrimidineacetic acid; 2,4,6-Trichloro-5-(carboxymethyl)pyrimidine; (2,4,6-Trichloro-5-pyrimidinyl)acetic acid; Pyrimidine-5-acetic acid, 2,4,6-trichloro-; 5-Acetic acid-2,4,6-trichloropyrimidine
EINECS	Contact for details

Quality Control

Our 2,4,6-Trichloro-5-(2-Acetic Acid) Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including research-grade to kilogram-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.