Description

n-(4-Aminobutyryl)-L-Histidine is a specialized dipeptide derivative that combines the structural motifs of L-histidine and 4-aminobutyric acid (GABA). This compound matters as a high-purity biochemical building block, offering precise molecular architecture for advanced research and development. It is primarily needed by pharmaceutical researchers and fine chemical manufacturers working on peptide-based therapeutics, enzyme inhibitors, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel peptide drugs and targeted therapeutic agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Neuroscience Probes: Employed in the development of compounds targeting neurotransmitter systems, given its histidine and GABA-related structure.
• Cosmeceutical Actives: Potential ingredient in advanced skincare formulations for its peptide-like properties.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in related chemical production.

Basic Information

Product Name	n-(4-Aminobutyryl)-L-Histidine
CAS No.	20314-38-9
Molecular Formula	C11H18N4O3
Molecular Weight	254.29 g/mol
Synonyms	N-(4-Aminobutanoyl)-L-histidine; L-Histidine, N-(4-aminobutanoyl)-; GABA-Histidine; 4-Aminobutyrylhistidine; γ-Aminobutyryl-L-histidine; (S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid 4-aminobutanoyl ester; Nα-(4-Aminobutyryl)histidine
EINECS	Contact for details

Quality Control

Our n-(4-Aminobutyryl)-L-Histidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range available on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.