Description

Ac-L-Leu-L-Ala-L-Phe-Oh is a synthetic tripeptide derivative, specifically an acetylated and C-terminal free acid form of the Leu-Ala-Phe sequence. This compound serves as a crucial building block and research standard in peptide chemistry and pharmaceutical development. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions for drug discovery, proteomics studies, and as a precursor for more complex peptide synthesis.

Application

• Pharmaceutical Intermediate: Used as a key building block in the synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies, particularly for protease and peptidase activity assays.
• Proteomics & Mass Spectrometry: Employed as a calibration standard or reference compound in analytical method development for peptide analysis.
• Medicinal Chemistry: Acts as a core structure for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Cosmetic Peptide Synthesis: Potential use as a precursor in the development of bioactive peptides for cosmetic and dermatological applications.

Basic Information

Product Name	Ac-L-Leu-L-Ala-L-Phe-Oh
CAS No.	20310-12-7
Molecular Formula	C₂₂H₃₃N₃O₅
Molecular Weight	419.52 g/mol
Synonyms	Ac-Leu-Ala-Phe-OH; Acetyl-Leucyl-Alanyl-Phenylalanine; Ac-L-Leu-L-Ala-L-Phe; N-Acetyl-L-leucyl-L-alanyl-L-phenylalanine; Ac-Leu-Ala-Phe; L-Phenylalanine, N-acetyl-L-leucyl-L-alanyl-; N-Acetyl-leucyl-alanyl-phenylalanine; Ac-Leu-Ala-Phe tripeptide
EINECS	Contact for details

Quality Control

Our Ac-L-Leu-L-Ala-L-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.