Description

H-Ala-Gly-Gly-Gly-Gly-OH is a synthetic pentapeptide consisting of one alanine and four glycine residues, with the CAS registry number 20296-73-5. This compound serves as a crucial building block and model substrate in peptide research and pharmaceutical development. It is primarily needed by research institutions, biotechnology companies, and pharmaceutical manufacturers engaged in peptide synthesis, biochemical studies, and the development of novel therapeutic agents.

Application

• Peptide Synthesis Building Block: Used as a key intermediate in the solid-phase or solution-phase synthesis of longer, more complex peptide sequences for research and development.
• Biochemical Research: Functions as a model substrate or standard in enzymatic studies, particularly for proteases and peptidases, to understand cleavage specificity and kinetics.
• Pharmaceutical Development: Employed in the preclinical research phase for developing peptide-based drugs, vaccines, and diagnostic agents.
• Structure-Activity Relationship (SAR) Studies: Serves as a core structure to investigate the impact of specific amino acid sequences on biological activity and stability.
• Academic Research & Teaching: Utilized in university laboratories for teaching advanced peptide chemistry and protein science principles.
• Bioconjugation: Acts as a spacer or linker molecule in the conjugation of peptides to other biomolecules, surfaces, or carriers.

Basic Information

Item	Detail
Product Name	H-Ala-Gly-Gly-Gly-Gly-OH
CAS No.	20296-73-5
Molecular Formula	C11H18N6O6
Molecular Weight	330.30 g/mol
Synonyms	Ala-Gly-Gly-Gly-Gly; AG4; H-Ala-Gly-Gly-Gly-Gly; Pentaglycylalanine; L-Alanyl-tetraglycine; Alanyl-tetraglycine; AG4 Peptide; 20296-73-5
EINECS	Contact for details

Quality Control

Our H-Ala-Gly-Gly-Gly-Gly-OH is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.