Description

H-Leu-Leu-Ala-Oh is a synthetic tripeptide composed of two leucine residues and one alanine residue with a free carboxylic acid terminus. This compound serves as a crucial building block and model substrate in biochemical and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the life sciences, peptide synthesis, and pharmaceutical development sectors for studying enzyme kinetics, metabolic pathways, and as an intermediate in the production of more complex bioactive peptides.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic assays, particularly for studying protease and peptidase activity.
• Pharmaceutical Intermediates: Serves as a key synthetic fragment in the development of novel therapeutic peptides and drug candidates.
• Proteomics & Metabolic Studies: Employed in research to understand protein digestion, amino acid transport, and metabolic pathways.
• Peptide Synthesis: Acts as a fundamental building block (amino acid sequence) in solid-phase or solution-phase peptide synthesis.
• Nutritional Science: Investigated for its potential role in protein nutrition and amino acid supplementation studies.
• Academic & Industrial R&D: A valuable tool for universities and chemical companies conducting basic and applied research in peptide chemistry.

Basic Information

Product Name	H-Leu-Leu-Ala-Oh
CAS No.	20274-80-0
Molecular Formula	C15H29N3O4
Molecular Weight	315.41 g/mol
Synonyms	L-Leucyl-L-leucyl-L-alanine; Leu-Leu-Ala; L-Leu-L-Leu-L-Ala-OH; H-LLa-OH; Tripeptide Leu-Leu-Ala; Alanyl-leucyl-leucine; N-(L-Leucyl)-L-leucyl-L-alanine; 2-[[2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]propanoic acid
EINECS	Contact for details

Quality Control

Our H-Leu-Leu-Ala-Oh is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure the material meets your research or production requirements. Our quality systems are designed to support applications demanding high levels of consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.