Description

Dl-2-Amino-3-Phosphonopropionic Acid is a phosphonic acid derivative of the amino acid aspartate, serving as a key biochemical research tool and synthetic intermediate. This compound is valued for its ability to act as a competitive antagonist at glutamate receptors, particularly the N-methyl-D-aspartate (NMDA) subtype, making it crucial for neurological and pharmacological studies. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and agrochemical sectors for investigating synaptic transmission and designing novel bioactive molecules.

Application

• Neuroscience Research: As a selective NMDA receptor antagonist to study excitatory neurotransmission, synaptic plasticity, and neurotoxicity.
• Pharmaceutical Development: A key intermediate in the synthesis of potential neuroprotective agents or drugs targeting glutamate pathways.
• Biochemical Studies: Used to investigate the role of phosphonate groups in enzyme inhibition and metabolic pathways.
• Agrochemical Research: Serves as a precursor or model compound for developing novel herbicides or plant growth regulators based on amino acid analogs.
• Chemical Synthesis: A versatile building block for creating more complex phosphonopeptides and other biologically active molecules.

Basic Information

Product Name	Dl-2-Amino-3-Phosphonopropionic Acid
CAS No.	20263-06-3
Molecular Formula	C₃H₈NO₅P
Molecular Weight	169.07 g/mol
Synonyms	DL-AP3; DL-2-Amino-3-phosphonopropanoic acid; DL-2-Amino-4-phosphonobutyric acid (historical); DL-2-Amino-4-phosphonobutanoic acid; (±)-2-Amino-3-phosphonopropionic acid; 2-Amino-3-phosphonopropionic acid; APPA; Phosphonoaspartic acid analog; NMDA receptor antagonist AP3
EINECS	243-672-1

Quality Control

Our Dl-2-Amino-3-Phosphonopropionic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.