Description

N(2),N(6)-Dipalmitoyllysine is a synthetic, lipophilic derivative of the essential amino acid lysine, where two palmitoyl groups are conjugated to the amino groups. This chemical modification is crucial for enhancing the lipid solubility and membrane permeability of bioactive compounds, making it a valuable intermediate in advanced formulation chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, cosmetic, and nutraceutical industries for developing novel drug delivery systems and functional ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of lipid-drug conjugates (LDCs) and prodrugs to improve bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Cosmetic & Personal Care Formulations: Used as a lipophilic moiety in the development of conditioning agents, emulsifiers, and active carriers in anti-aging and moisturizing skincare products.
• Nutraceutical & Food Supplement Research: Investigated for creating novel lipid-based delivery systems for vitamins, amino acids, and other nutrients to enhance absorption.
• Bioconjugation & Biochemical Research: Serves as a reagent for modifying peptides, proteins, and other biomolecules to study cellular uptake mechanisms and create new bioprobes.
• Liposome & Nanoparticle Technology: A functional component in the design and preparation of lipid nanoparticles (LNPs) and liposomal carriers for targeted delivery applications.
• Surfactant & Emulsion Science: Acts as a non-ionic surfactant or co-emulsifier in specialized emulsion systems requiring specific fatty acid profiles.

Basic Information

Product Name	N(2),N(6)-Dipalmitoyllysine
CAS No.	20257-67-4
Molecular Formula	C38H74N2O4
Molecular Weight	622.99 g/mol
Synonyms	Nα,Nε-Dipalmitoyl-L-lysine; Lysine, N2,N6-bis(1-oxohexadecyl)-; L-Lysine, N2,N6-bis(1-oxohexadecyl)-; Dipalmitoyl Lysine; N,N-Bis(palmitoyl)-L-lysine; N-Palmitoyl-L-lysine N-palmitamide; Lysine dipalmitate; N2,N6-Dihexadecanoyllysine
EINECS	Contact for details

Quality Control

Our N(2),N(6)-Dipalmitoyllysine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.