Description

S-Thiopental is a thiobarbiturate derivative, a key chemical intermediate in pharmaceutical research and development. Its primary value lies in its role as a precursor for synthesizing specialized anesthetic and central nervous system (CNS) agents. This compound is essential for R&D laboratories and manufacturers in the pharmaceutical and fine chemical sectors focusing on neuropharmacology and anesthetic drug development.

Application

• Pharmaceutical Intermediate: Primary use as a building block for the synthesis of thiobarbiturate-based anesthetic agents.
• Research & Development: Critical material in medicinal chemistry for studying structure-activity relationships (SAR) of barbiturate analogs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Studies: Used in preclinical research to investigate mechanisms of action related to GABAA receptor modulation.
• Fine Chemical Synthesis: Intermediate for creating more complex, specialized molecules in custom synthesis projects.

Basic Information

Product Name	S-Thiopental
CAS No.	20224-43-5
Molecular Formula	C11H18N2O2S
Molecular Weight	242.34 g/mol
Synonyms	Thiopental Impurity C; 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric Acid; Thiopental Related Compound C; Penthiobarbital; Thiopenal; NSC 76098; 2-Thiobarbituric acid, 5-ethyl-5-(1-methylbutyl)-; 5-Ethyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
EINECS	Contact for details

Quality Control

Our S-Thiopental is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data supporting identity, purity, and impurity profiles. A Certificate of Analysis (COA) is supplied with each batch, detailing results from tests including HPLC assay, related substances, residual solvents, and identification. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.