Description

n-Methyl-2-Nitro-4-(Trifluoromethyl)Aniline is a specialized aromatic amine derivative featuring both nitro and trifluoromethyl functional groups. This compound serves as a crucial advanced intermediate in the synthesis of complex molecules, valued for its ability to introduce specific electronic and steric properties. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Dye and Pigment Precursor: Serves as an intermediate in the production of specialized azo dyes and high-performance pigments for industrial applications.
• Liquid Crystal and OLED Material Research: Employed in the development of organic electronic materials due to its electron-withdrawing nitro and trifluoromethyl substituents.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.
• Polymer Modification: Used to functionalize polymers, imparting specific chemical resistance or surface properties.

Basic Information

Product Name	n-Methyl-2-Nitro-4-(Trifluoromethyl)Aniline
CAS No.	20200-22-0
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	2-Nitro-N-methyl-4-(trifluoromethyl)aniline; N-Methyl-2-nitro-4-(trifluoromethyl)benzenamine; 4-(Trifluoromethyl)-2-nitro-N-methylaniline; Benzenamine, N-methyl-2-nitro-4-(trifluoromethyl)-; 2-Nitro-α,α,α-trifluoro-p-toluidine; N-Methyl-α,α,α-trifluoro-2-nitro-p-toluidine; 1-Methylamino-2-nitro-4-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our n-Methyl-2-Nitro-4-(Trifluoromethyl)Aniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports your cGMP and ISO-aligned processes for reliable scale-up and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.