Description

2-Chloro-8-Methoxyquinazolin-4(3H)-One is a high-value, multi-functional quinazolinone derivative that serves as a critical synthetic intermediate. Its molecular structure makes it a versatile building block for constructing more complex heterocyclic compounds, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic frameworks for material science and specialty chemical applications.
• Biochemical Tool Compound: Serves as a scaffold for developing probes and inhibitors in biochemical and pharmacological studies.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized quinazolinone-based colorants.

Basic Information

Product Name	2-Chloro-8-Methoxyquinazolin-4(3H)-One
CAS No.	20197-99-3
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	2-Chloro-8-methoxy-4(3H)-quinazolinone; 2-Chloro-8-methoxyquinazolin-4-ol; 4(3H)-Quinazolinone, 2-chloro-8-methoxy-; 8-Methoxy-2-chloro-4(3H)-quinazolinone; 2-Chloro-8-methoxy-3,4-dihydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-Methoxyquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.