Description

Norvaline,3-Hydroxy-2,4-Dimethyl-,Dl-Threo-(8Ci) is a specialized, non-proteinogenic amino acid derivative with a unique stereochemical configuration. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the development of complex molecules with precise structural control. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors for applications ranging from drug discovery to the synthesis of bioactive peptides and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic pathways.
• Peptide Synthesis: Used to incorporate non-standard amino acid residues into synthetic peptides, modifying their stability, bioavailability, and biological activity for therapeutic and research purposes.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway analysis, helping to elucidate biological mechanisms.
• Asymmetric Synthesis: Acts as a precursor or auxiliary in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including advanced ligands for catalysis and custom-designed molecular scaffolds.
• Nutritional Science Research: Investigated for its potential effects on amino acid metabolism and related physiological processes.

Basic Information

Item	Detail
Product Name	Norvaline,3-Hydroxy-2,4-Dimethyl-,Dl-Threo-(8Ci)
CAS No.	20192-83-0
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	DL-threo-3-Hydroxy-2,4-dimethylnorvaline; (±)-threo-3-Hydroxy-2,4-dimethylnorvaline; 2,4-Dimethyl-3-hydroxynorvaline; 3-Hydroxy-2,4-dimethyl-DL-norvaline; α-Amino-β-hydroxy-2,4-dimethylvaleric acid; 3-Hydroxy-2,4-dimethylpentanoic acid, 4-amino-; (2R,3S)-rel-3-Hydroxy-2,4-dimethyl-4-aminopentanoic acid
EINECS	Contact for details

Quality Control

Every batch of our Norvaline,3-Hydroxy-2,4-Dimethyl-,Dl-Threo-(8Ci) is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for research and fine chemical use. Comprehensive analytical testing, including HPLC for purity and chiral analysis for stereochemical confirmation, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	DL-threo mixture as specified
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.