Description

Isovaline, 3-Hydroxy-, (R*,R*)- (9Ci) is a non-proteinogenic amino acid derivative of significant interest in advanced chemical synthesis and research. This compound serves as a valuable chiral building block and intermediate for the development of novel pharmaceuticals, bioactive peptides, and complex organic molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptidomimetics, metabolic studies, and the synthesis of specialized amino acid analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics to alter biological activity, stability, or receptor binding profiles.
• Biochemical Research: Serves as a standard or probe in metabolic pathway studies and enzyme-substrate interaction research due to its unique structure.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective organic synthesis to induce desired stereochemistry.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Isovaline, 3-Hydroxy-, (R*,R*)- (9Ci)
CAS No.	20182-77-8
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	3-Hydroxyisovaline; (R*,R*)-3-Hydroxy-3-methylbutanoic acid 2-ammonium salt; 2-Amino-3-hydroxy-3-methylbutanoic acid; 3-Methyl-3-hydroxy-2-aminobutanoic acid; β-Hydroxyisovaline; 3-Hydroxy-3-methyl-DL-2-aminobutanoic acid; 2-Amino-3-hydroxy-3-methylbutyric acid
EINECS	Contact for details

Quality Control

Our Isovaline, 3-Hydroxy-, (R*,R*)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation or clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.