Description

Amino Acid Hydroxamates Dl-Aspartic Acid β-Hydroxamate Monohydrate is a specialized derivative of aspartic acid, where the carboxylic acid group is converted to a hydroxamic acid functionality. This structural modification is critical for its role as a potent and selective inhibitor of various metalloenzymes, particularly those utilizing zinc or other metal ions in their active sites. It is an essential research chemical and biochemical tool for scientists in pharmaceutical development, agricultural chemistry, and fundamental enzymology studies. The compound is supplied as a monohydrate salt to enhance its stability for storage and handling.

Application

• Enzyme Inhibition Studies: Primarily used as a research-grade inhibitor for aspartate-semialdehyde dehydrogenase, glutamine synthetase, and other ammonia-assimilating enzymes in biochemical and microbiological research.
• Pharmaceutical Research: Serves as a key intermediate or pharmacophore in the discovery and development of novel therapeutic agents targeting bacterial, fungal, or plant pathogens.
• Agricultural Chemistry: Investigated for its potential herbicidal or plant growth regulation properties by interfering with essential amino acid biosynthesis in plants.
• Biochemical Tool Compound: Utilized in laboratory settings to study metabolic pathways, specifically the biosynthesis of essential amino acids like lysine, threonine, and methionine in microorganisms and plants.
• Chelation Research: Acts as a model compound for studying the chelating properties of hydroxamate groups towards di- and trivalent metal ions (e.g., Fe³⁺, Zn²⁺).

Basic Information

Product Name	Amino Acid Hydroxamates Dl-Aspartic Acid β-Hydroxamate Monohydrate
CAS No.	20154-32-9
Molecular Formula	C₄H₈N₂O₅ • H₂O
Molecular Weight	182.13 g/mol (Monohydrate)
Synonyms	DL-Aspartic acid β-hydroxamate monohydrate; DL-Aspartic β-hydroxamic acid monohydrate; 2-Amino-3-(hydroxycarbamoyl)propanoic acid monohydrate; DL-2-Aminosuccinamic acid N-hydroxy monohydrate; Aspartic acid hydroxamate; ASAH; β-Aspartohydroxamic acid monohydrate
EINECS	Contact for details

Quality Control

Our Amino Acid Hydroxamates Dl-Aspartic Acid β-Hydroxamate Monohydrate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	Theoretical (Monohydrate)
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.