Description

Angiotensin Acetate is a high-purity synthetic peptide derivative of the endogenous hormone angiotensin, widely utilized in biochemical and pharmaceutical research. This compound is critical for studying the renin-angiotensin system (RAS), which regulates blood pressure and fluid balance. It serves as a key reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the life sciences, particularly in cardiovascular and renal disease research, drug discovery, and diagnostic assay development.

Application

• Biomedical Research: Used as a precise biochemical tool for investigating angiotensin receptor (AT1 & AT2) signaling pathways, mechanisms of vasoconstriction, and aldosterone secretion.
• Pharmaceutical Development: Serves as a critical reference standard and intermediate in the synthesis and quality control of novel cardiovascular therapeutics targeting hypertension and heart failure.
• Diagnostic Assays: Employed in the calibration and validation of immunoassay kits (e.g., ELISA, RIA) for the quantitative measurement of angiotensin peptides in biological samples.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study cellular responses, receptor binding affinity, and the physiological effects of angiotensin peptides under controlled conditions.
• Academic & Institutional Research: A fundamental reagent in university and institutional labs for physiological studies related to blood pressure regulation, kidney function, and endocrine research.

Basic Information

Product Name	Angiotensin Acetate
CAS No.	20071-00-5
Molecular Formula	C49H69N13O11 • (C2H4O2)x
Molecular Weight	~1046.2 g/mol (Free base)
Synonyms	Angiotensin II Acetate; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Acetate; DRVYIHPF Acetate; [Asp1, Val5]-Angiotensin II Acetate; All-L-Angiotensin II Acetate; Hypertensin Acetate; Ang II Acetate; Human Angiotensin II Acetate
EINECS	Contact for details

Quality Control

Our Angiotensin Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, Mass Spectrometry (MS) for identity confirmation, and Amino Acid Analysis (AAA). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/Titration)	Contact for details
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.