Description

4,5-Dichloro-2-Fluorophenol is a halogenated phenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active ingredients, fine chemicals, and functional materials who require high-purity, reliable intermediates.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides where the dichloro-fluorophenol moiety imparts specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic display and lighting applications.
• Polymer & Resin Modifiers: Acts as a monomer or additive to introduce halogenated phenolic groups, enhancing flame retardancy or other material properties.
• Dyestuff & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments requiring halogenated aromatic backbones.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	4,5-Dichloro-2-Fluorophenol
CAS No.	2995-08-6
Molecular Formula	C6H3Cl2FO
Molecular Weight	180.99 g/mol
Synonyms	2-Fluoro-4,5-dichlorophenol; 4,5-Dichloro-2-fluorophenol; 2-Fluoro-4,5-dichloro-1-hydroxybenzene; Phenol, 4,5-dichloro-2-fluoro-; 4,5-Dichloro-2-fluoro-1-hydroxybenzene; 1-Hydroxy-4,5-dichloro-2-fluorobenzene
EINECS	Contact for details

Quality Control

Our 4,5-Dichloro-2-Fluorophenol is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging, or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	65 - 69 °C
Loss on Drying	≤0.5%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.