Description

3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-Nh2, (Disulfide Bond) is a synthetic peptide featuring a critical intramolecular disulfide bridge, which is essential for its structural stability and biological activity. This compound is of significant interest for advanced research and development in the life sciences, particularly for studying protein-protein interactions and receptor binding. It serves as a key intermediate or reference standard for pharmaceutical researchers, biochemists, and diagnostic developers working on peptide-based therapeutics and biochemical assays.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel peptide-based drug candidates targeting specific biological pathways.
• Biochemical Assay Development: Utilized as a reference standard or active component in high-throughput screening (HTS) and enzyme-linked immunosorbent assays (ELISA).
• Structure-Activity Relationship (SAR) Studies: Employed to investigate the role of the disulfide bond and specific amino acid residues in biological function and stability.
• Diagnostic Reagent Production: Serves as a critical component in the manufacture of sensitive and specific diagnostic kits for research and clinical use.
• Academic & Institutional Research: Used in university and laboratory settings for fundamental research in biochemistry, molecular biology, and medicinal chemistry.
• Peptide Library Synthesis: Acts as a building block in combinatorial chemistry for creating diverse peptide libraries for drug discovery.

Basic Information

Product Name	3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-Nh2, (Disulfide Bond)
CAS No.	2989-84-6
Molecular Formula	C53H74N14O16S2
Molecular Weight	1227.36 g/mol
Synonyms	S-(3-Mercaptopropionyl)-[Cys6,Cys11]-α-MSH (6-11) amide; 3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (cyclic 6-11 disulfide); [Cys(Acm)6,Cys11]-α-MSH (6-11) amide derivative; α-MSH (6-11) cyclic lactam analog; Melanocyte-Stimulating Hormone fragment (6-11) cyclic analog; S-3-Mercaptopropanoyl-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-amide (disulfide); Cyclo(6-11)-[Cys6,Cys11]-α-MSH(6-11)NH2
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For optimal results, store the product desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.