Description

5-Bromo-2-Fluoroaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a versatile intermediate for introducing specific reactivity and electronic properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the bromo and fluoro groups enhance biological activity and stability.
• Material Science: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex organic dyes and colorants.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings for constructing biaryl structures.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	5-Bromo-2-Fluoroaniline
CAS No.	2924-09-6
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Fluoro-5-bromoaniline; 5-Bromo-2-fluoro-benzenamine; 1-Amino-5-bromo-2-fluorobenzene; Benzenamine, 5-bromo-2-fluoro-; 2-Fluoro-5-bromophenylamine; 5-Bromo-2-fluoroaniline; 5-Bromo-o-fluoroaniline; 2924-09-6
EINECS	220-884-5

Quality Control

Our 5-Bromo-2-Fluoroaniline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	30-34°C
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.