Description

L-Kynurenine is a key endogenous metabolite in the tryptophan degradation pathway, serving as a critical biochemical intermediate. Its significance lies in its role as a precursor to several neuroactive compounds, including kynurenic acid and quinolinic acid, making it essential for research into neurological and immunological functions. This product is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in neuroscience, metabolic studies, and as a reference standard.

Application

• Biochemical Research: Used as a critical intermediate in studies of the kynurenine pathway, neuroinflammation, and neurodegenerative diseases.
• Pharmaceutical Development: Serves as a reference standard and starting material for the synthesis of novel therapeutic agents targeting neurological and immunological disorders.
• Cell Culture & In Vitro Studies: Employed in metabolic pathway analysis and to modulate cellular responses in immunological and cancer research.
• Diagnostic Reagent Manufacturing: Utilized in the production of assay kits and reagents for quantifying tryptophan metabolites in biological samples.
• Academic Research: Fundamental tool in university and institutional labs for investigating metabolic disorders and redox biology.

Basic Information

Product Name	L-Kynurenine
CAS No.	2922-83-0
Molecular Formula	C10H12N2O3
Molecular Weight	208.21 g/mol
Synonyms	L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; Kynurenine, L-; (-)-Kynurenine; (S)-Kynurenine; L-(-)-Kynurenine; Kynurenine
EINECS	220-869-7

Quality Control

Our L-Kynurenine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-30.0° to -34.0° (c=1 in 1N HCl)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.